통합검색

College of Science - Biological Sciences

게시글 검색
All
BAE, YOE SIK 사진 more
  • Professor
  • BAE, YOE SIK

[Research Interest]

We are interested in the development of bioactive molecules that can be used to treat infectious or inflammatory diseases. Our major target diseases include polymicrobial sepsis, rheumatoid arthritis, inflammatory bowel disease, and colon cancer. To generate useful target molecules that can be used to develop therapeutic agents against these infectious or inflammatory diseases, we are focusing on several chemoattractant G-protein coupled receptors (GPCRs). Since leukocyte trafficking in vivo is a crucial event that modulate immune and inflammatory responses, and chemotactic GPCRs mediate these response, the receptors can be considered as important primary targets to control infectious or inflammatory disorders. Currently, we are testing the effects and mechanism of action of chemotactic GPCR ligands against these diseases in experimental animal models.

CHO, HONGBAEK 사진 more
  • Associate Professor
  • CHO, HONGBAEK
    Lab

[Research Interest]

Bacterial cell wall assembly Maintenance of cell envelope integrity during assembly of trans-envelope complexes Antibiotic resistance and persistence

CHOI, CHEOLYONG 사진 more
  • Professor Molecular Genetics
  • CHOI, CHEOLYONG 홈페이지 바로가기
    Lab Lab of Molecular Genetics

[Research Interest]

Phosphorylation and ubiquitination are reversible post-translational modifications with key roles in various signal transduction cascades. Currently, cancer cell-specific metabolic adaptation is a hot issue to be addressed. The mammalian target of rapamycin (mTOR) signaling pathway integrates both intracellular and extracellular signals and serves as a central regulator of cell metabolism, growth, proliferation and survival. The mTOR pathway is activated during various cellular processes such as tumor formation and angiogenesis, insulin resistance, adipogenesis and is deregulated in human diseases such as cancer and diabetes. Although ubiquitination of target protein plays a critical role in other cellular activity during tumorigenesis, little is known about functional relevance of ubiquitin-mediated coordination of mTOR pathway and autophagy induction. So we have interested in the deciphering molecular networks of signaling pathway particularly associated with human diseases caused by malfunction of nutrient sensing.

JUNG, JAE HOON 사진 more
  • Associate Professor Plant Biochemistry
  • JUNG, JAE HOON
    Lab Plant Biochemistry Lab

[Research Interest]

Role of plant prion-like proteins in temperature sensing Plant temperature sensing mechanism through the process of phase separation Role of reactive oxygen species in transmitting temperature signals

JUNG, SUMYUNG 사진 more
  • Associate Professor Metabolic Biochemistry, Molecular Cell Biology
  • JUNG, SUMYUNG

[Research Interest]

1. Adipose tissue’s nutrient utilization and its roles in systemic metabolic homeostasis. 2. Mechanisms by which nutrient sensing pathways regulate metabolism. 3. Crosstalk between signaling and metabolism.

KIM, CHEORL-HO 사진 more
  • Professor Molecular Glycobiology
  • KIM, CHEORL-HO 홈페이지 바로가기
    Lab Molecular and Cellular Glycogiology

[Research Interest]

Research interests are the field of glycomics and glycobiology, expecially on sphingolipid, ceramide and sialic acid-containing sphingolipids, ganglioside. Academic findings: Hepatic B Viral hepatocarcinoma and PTEN (Cancer Res 2003), asialo-1 acid glycoprotein in liver cirrhosis and carcinoma (Hepatol Res, 2003), GlcNAc:βMan1,4GlcNAcT-III in hepatitis (Glycoconj J, 2003), MMP-9/2 and α-fetoproteins in HBV hepatitis (J. Gastroent Hepatol 2004), HBV metastatic (FASEB J. 2004), Hepatic GnT-V and GnT-III-ApoB100 (JBC. 2004), Disialo GD3 in VSMC (JBC. 2004), therapeutic hepatocarcinoma cells (FASEB J. 2004), TG-2 in leukemia (FEBS Lett. 2004), N-GlcNAcT-III in HBV (J Gastroent Hepatol, 2004), Monosialyl GM3 in leukemic differentiation (Glycobiology 2005), MMP-9 in IVF (British J Obstetrics and Gynecol. 2005), disialo GD3 Fas-T cells (Glycobiology 2006), GM3 in PTEN (Glycobiology 2006), ROS in sialic GD3-cell (FASEB J 2006), AP-2a in GM3-PTEN (Glycobiology 2008), sialidase in leukemia (BBA 2008), GM3-VEGFR-2 interaction (Glycobiology 2009), GD3 in breast cancer (Biological Chemistry 2009), pig CMAH and N-glycolylneuraminic acid (Biochem J 2010), pST6GalNAc IV for Neu5Aca2-3Galb1-3GalNAc (Glycoconj J 2011), GM3 in TGF-β1-induced EMT (Biochem J. 2013), VEGFR-2 in neovascularization (J Mol Medicine 2013), monosialyl GM3 (Plos One 2014) and TGF-receptor (Int. J. of Biochem. Cell Biol. 2014), Sialyl Le A/X of HBx (Mol Cancer 2014, J Cell Biochem 2015). Housekeeping promoter 5'pcmah-2 of CMP-NeuGc gene (Glycoconj 2016), GD1b Apoptosis of MCF-7 (IJMS 2016), Human ST8Sia VI (α2,8-Sialyltransferase) Gene (IJMS 2016), GD2-ICAMI (IJMS 2017), Sialyllactose VEGFR-2 activation, GD3/a1AR/TG2, AApoB100-GM3, GM3-macrophage (JCB, 2017, 2018), Sirt1-FcεRI- mast cell AMPK (Sci Rep, 2017), ASC/LPS (PloS One 2017), 4-o-cASC (JCB, JSMB 2018), SARS-CoV-2-sialylation. Lectin-Glycan (IJMS, 2020),CMP-NeuGc (Sci Rep 2019), AC (FP), 3-SL-sIGLEC (Glycoconj J 2020), Avc(FP, 2021, IJMS 2021).

KIM, HONG SOOK 사진 more
  • Associate Professor
  • KIM, HONG SOOK
  • Natural Sciences 2 1F 32110

[Research Interest]

cancer biology, developmental biology, epigenetics, genomics, precision medicine, gene regulation

KIM, JEONGHA 사진 more
  • Professor
  • KIM, JEONGHA 홈페이지 바로가기

[Research Interest]

Marine Ecology Laboratory of Sungkyunkwan University carries out a variety of research projects concerning Korean marine environments, which include 1) ecological monitoring of marine benthic habitats with regard to global warming and seawater temperature changes, 2) population ecological works of introduced species and endangered species for their conservation perspectives, 3) molecular ecological works on populations of seaweeds and marine invertebrates, 4) urchin barrens (백화현상) and recovery of kelp forest. Most of these projects have been conducted with international and domestic research co-work teams. Researches in my lab covers from field experimental works to molecular ecological works.

KIM, JINSUB 사진 more
  • Associate Professor
  • KIM, JINSUB
  • +82-31-290-7014
  • Natural Sciences 2 3F 32362

[Research Interest]

Computational neuroscience of Connectomics. Connectome is the entire synaptic connections of all the neurons in the brain. A Connectome is equivalent to the identity of an individual, since it is the origin of all the brain functions including cognition, memory, and personality. Computational neuroscience regards the neural circuits as biological computers and study the mathematical principles on which the brain works. Finding the working principles of the brain together with the differences of individuals will lead to the complete understanding of ourselves. Toward these ultimate goals, we investigate the neural connectivity and activity from electron microscope brain images and other experiment data using computer technologies including artificial intelligence. Current projects cover various brain regions for various brain functions, including the retina for perception, the cerebral cortex for cognition, and the cerebellar cortex for motion control.

KIM, JIYUN 사진 more
  • Assistant Professor
  • KIM, JIYUN
  • +82-31-290-7004
  • Natural Sciences 2 1F 32114
KIM, JUNHO 사진 more
  • Associate Professor bioinformatics, computational genomics
  • KIM, JUNHO

[Research Interest]

Computational genomics, Bioinformatics, NGS analysis and method development, Somatic mutation analysis, Single cell genomics

KIM, SEUNG CHUL 사진 more
  • Professor
  • KIM, SEUNG CHUL 홈페이지 바로가기
    Lab Plant Molecular Phylogenetics Laboratory

[Research Interest]

I am primarily interested in systematics and evolutionary biology of plants. In particular, I am interested in the origin and evolution of plant endemics on oceanic islands, including the Macaronesian Islands in the Atlantic Ocean and Jeju and Ulleung Island in Korea. I am also interested in revealing complex evolutionary history of polyploidy and homoploidy lineages of flowering plants. Additional research interests include conservation genetics of rare and endangered species, population genetics of invasive weedy species, ethnobotany, plant domestication, and phylogeography of east Asian plants. A variety of techniques and molecular markers are utilized to unravel the phylogenetic patterns and underlying processes generating plant diversity.

KWON, JAEYOUNG 사진 more
  • Professor Molecular Neurogenetics
  • KWON, JAEYOUNG 홈페이지 바로가기
    Lab Neurogenetics lab

[Research Interest]

All animals are born with a set of instincts, or innate behaviors, and our main questions are how complex behaviors are organized in the nervous system and how they are programmed during development. For this, the chemosensory system would be one of the most excellent models. Smell and taste are known to be important for sensing predators, selecting mates as well as finding food. We would like to trace the neuronal pathways that mediate a complex instinctive behavior such as feeding, from sensory input through to motor output. We are using the fruit fly as a model system to study chemosensation.

LEE, DAEHAN 사진 more
  • Assistant Professor
  • LEE, DAEHAN
  • +82-31-290-5923
LEE, JAE-SEONG 사진 more
  • Professor Molecular and environmental biology
  • LEE, JAE-SEONG
  • 2021 SKKU Fellowship

[Research Interest]

Epigenetics, Host-microbiome interaction, Ocean acidification, Microplastic, Hypoxia

LEE, SANGHO 사진 more
  • Professor Structural Biology
  • LEE, SANGHO 홈페이지 바로가기
    Lab Laboratory of Biomolecular Architecture

[Research Interest]

Life is controlled by a milieu of macromolecular interactions. We focus on understanding structural basis for protein interactions and their applications using a variety of biophysical and biochemical techniques such as crystallography and solution scattering as well as standard techniques in molecular cell biology. We study proteins interactions in ubiquitin signaling, host-pathogen relationship and abiotic stress response signaling. We also develop mini-antibody based bionano sensors for both diagnostic and therapeutic purposes.

LIM, WHASUN 사진 more
  • Associate Professor
  • LIM, WHASUN
    Lab 분자발생학 및 세포신호전달연구실

[Research Interest]

Cell signaling, molecular development, molecular pharmacology, toxicology, reproductive medicine

PARK, SEOKHEE 사진 more
  • Professor
  • PARK, SEOKHEE 홈페이지 바로가기

[Research Interest]

TGF-beta is a pivotal cytokine which is involved in a variety of cellular functions. Our group has been focused on the signaling pathways mediated by TGF-beta superfamily cytokines regarding cancer progression and anti-inflammation during the past decade. Our current research focuses on the identification of novel mechanism of TGF-beta or BMP-mediated tumorigenesis and metastasis. In addition, we are also doing the studies about how specific signaling pathways in the inflammation and cancer biology are regulated by ubiquitination and deubiquitinating mechanism. Through these diverse approaches, the final goal in our group is to understand the molecular mechanisms regarding cancer and inflammation and subsequently to identify therapeutic target proteins to treat cancer and inflammation.

YANG, SI YOUNG 사진 more
  • Associate Professor
  • YANG, SI YOUNG
YOON, HWAN SU 사진 more
  • Professor
  • YOON, HWAN SU
    Lab Evolutionary Genomics Lab

[Research Interest]

Hwan Su Yoon is an Associate Professor in the Department of Biological Sciences at Sungkyunkwan University, Korea. He received his PhD in biology from Chungnam National University. After research training at the University of Iowa, he worked at the Bigelow Laboratory for Ocean Sciences. His research interests include eukaryotic biodiversity, phylogeny, single cell genomics, and genome evolution, with a focus on red algae and red algal plastid descendants (e.g., the cryptophytes, haptophytes, stramenopiles, and dinoflagellates).